Unlocking the full potential of the gut microbiome
MRM Health's proprietary CORAL® platform allows to harness the full power of the gut microbiome to develop effective and safe therapeutics by combining rationally selected strains into Optimized Consortia through a proprietary optimization process and a unique manufacturing strategy as single Drug Substance
MRM Health in brief
Clinical-stage biotech (Belgium, 2020) developing innovative microbiome-based Live Biotherapeutic Products
for chronic diseases with high unmet needs.
Disruptive CORAL® technology for design and manufacturing of disease-focused microbial consortia
with enhanced efficacy and scalability.
Best-in-class therapeutics for inflammatory diseases and beyond, with excellent safety and disease-modifying potential.
Advanced clinical program in Inflammatory Bowel Diseases (IBD), with positive clinical data in Phase 2a trials showing safety and efficacy in both mild-to-moderate ulcerative colitis and in the orphan disease indication pouchitis.
Preclinical programs in other inflammatory diseases and in immune-oncology.
Based on two decades of experience in microbiome R&D
MRM Health is based in a Center of Expertise for microbiome research and development in the biotech cluster in Ghent and has a strategic partnership with the the leading life sciences institute VIB, with top research groups in both microbiome analysis and ecology and in host biology and disease research.
Corporate VideoCORAL® platform
Through its differentiating technology platform, MRM Health develops Optimized Consortia, a novel class of microbial therapeutics which surpass the current microbiome approaches. Using a bioinformatics-guided in-human discovery engine, key therapeutic strains are identified and integrated into Optimized Consortia through its proprietary Microbiome Optimization Technology. The Company’s breakthrough GMP-compliant manufacturing technology allows to manufacture complete therapeutic consortia as a single Drug Substance.
With its impressive consortia optimization and manufacturing technology, MRM Health disrupts exactly there where others stumble.
Prof. Jeroen Raes, KOL Gut Microbiome VIB-KULeuven, Belgium
CORAL® platform
Fully characterized consortia of specific combinations of disease-focused safe & effective strains
Optimized and primed for sustained impact on disease
Faster onset-of-action & superior efficacy profile
Breakthrough manufacturing as single Drug Substance with reduced complexity & cost-of-goods
Differentiating regulatory status
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Strong industrial and financial support
MRM Health is strategically supported by strong international and local investors, including Biocodex, ATHOS, SFPIM, Ackermans & van Haaren, OMX Europe Venture Fund, Qbic II, BNP Paribas Private Equity, IFF and VIB. The company has corporate collaborations within and beyond pharma applications and has additional therapeutic areas available for partnering.
Development capabilities
MRM Health features End-to-End development capabilities, from discovery to CMC, regulatory and clinical development. We have direct access to the most advanced simulator of the human gut, the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®). In addition, through strategic partnerships with international research centers, MRM Health has secured extensive complementary microbiome and bioinformatics capabilities, multidisciplinary knowhow and patient insights.
