Our Technology

Gut microbiome in Health and Disease

We are 30 trillion human cells and 100 trillion microbial cells. These microbial communities play critical roles in supporting life and health. The microbiome is the collective genome of organisms that live in, on and around us, sometimes referred to as the forgotten organ. It plays a key role in health and disease. Dysbiosis is both a cause as well as an indicator of disease.

The new paradigm in medicine: microbiome therapeutics

The microbiome acts as master regulator of the immune system. The gut microbiota plays a fundamental role in local and systemic immunity and homeostasis. The host-microbe interaction leads to fine-tuned regulation of innate and adaptive immune repsonses. The modulation of the severity of a disorder through dietary interventions and their influence on microbiome–immune interactions is an exciting area of research.

microbiome targeted therapeutics immunology IBD neurology rheumatology

Our technology - SHIME®
Simulator of the Human Intestinal Microbial Ecosystem

  • Most advanced simulator of the human gut on the market
  • Allows to model the complete intestine in the lab
  • Direct insight into intestinal processes
  • Complete intestinal microbiome in natural environment
  • Modeling of intake and digestion of food and pharmaceuticals
  • Simulator of the Human Intestinal Microbial Ecosystem
    Microbiome therapeutics technology research in novel medicines

    MRM Health’s breakthrough R&D

    We develop synthetic consortia of bacteria with defined composition. Our proprietary process ensures optimized composition, capable of effective engraftment in vivo, rapid onset of action, with a range of robust and superior functional responses.

    Patient-driven strain selectiony

    isolation and characterization of strains based on unique clinical datasets and in-human discovery approaches, in combination with access to proprietary strain libraries.

    Microbial Resource Management (MRM)

    Rational design and optimization into defined synergistic multi-strain bacterial consortia.

    Proprietary optimization process

    resulting in oral formulation with improved engraftment and functional responses and in superior efficacy in restoration of microbial metabolic networks and host-disease endpoints.

    Microbiome specialists

    Unique and differentiating platform for the discovery and development of novel microbiome-based therapeutics to overcome critical bottlenecks currently hampering microbiome-based product development.

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